It starts out as a nice day at clinicals. Your nurse is happy to be working with you – bonus. You were prepared, organized and your morning is going nice and smooth. You go in to check on your previously alert and oriented patient…. and they are no longer very alert and no longer oriented. NOW WHAT? …although you will need to get your nurse and/ or instructor, what should you be thinking about in a patient with new onset of acute confusion? And in reality, one day you will be that nurse, so let’s learn what to do now!